Ibogaine refers to the alkaloid which is obtained from root bark of special types of plants. These shrubs are called Tabernanthe Iboga. They develop mainly within the rain forests found within the West of Central areas of African continent. These shrubs have medicine values. That means that ibogaine treatment is important in management of specific illnesses that affect people.
This alkaloid occurs in different formulations. In some places, the root bark is just chewed and swallowed in greater amounts in order to produce the desired psychoactive effects. Some are found in crystalline form while others are synthetic derivatives, such as 18-methoxycoronaridine.
The most common formulation of this drug is Ibogaine Hydrochloride, shortened as Ibo HCl. This form is stabilized by salt and occurs in form of white powder. It gets usually supplied in form of capsules that can have variable colors.
Some providers make the drug using complete extracts of alkaloids usually contained in the root covers of given shrubs. However, the quantity of the Ibogaine in these samples varies from 8% up to 10%. The amount may also differ from batch to batch.
This method of treatment is applied in curing several health states. Such conditions comprise opioid dependence, prolonged pain as well as psychotherapy. Further disorders comprise bulimia, phobias, depression, anxiety, post-traumatic stress disorder and stress.
It is administered to the body orally. The dose varies with age and the weight of the patient that is using it. However, the standard doses range from 5mg/kg to 30 mg/kg of the weight of the body. This means that any dose that is greater than 30mg/kg of body weight is likely to cause the undesired effects.
It takes only 40-60 minutes before one begins experiencing its effects once he or she has taken this drug. Besides, the peak for the effects lasts for about 2 hours. During this peak, one is commonly in a dream-like condition though his or her consciousness in time, space and person is usually maintained.
This drug is a form of tryptamine. Therefore, it exerts its effects by binding to the serotonin receptors and up regulating their activity. Besides, it also binds to the glutamate receptors as well as k-opioid receptors hence antagonizing their activity. This property makes it unique from the other known tryptamines and agonists of serotonergic receptors.
This alkaloid is processed in the liver in the human beings with use of the special kinds of the enzymes known as cytochrome P450. The enzymes catalyze several reactions within the body. Once this drug is metabolized noribogaine which is much potent compared to ibogaine is released. It causes greater psychoactive effects. Finally, it is excreted from the body through the kidneys.
It has several side effects. They involve difficulty in coordinating movement of quite a number of muscles within the body, nausea, a dry mouth and spewing. It may also alter the usual operation of the heart.
The legal standing of ibogaine treatment differs from nation to nation. Some nations have illegalized it whereas others still allow its use. However, for those still using it, it must be given by a physician under tight regulation. This is for the reasons of its side effects.
You can visit the website www.ibogapath.com for more helpful information about Find Out More About Ibogaine Treatment
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